Consumers engage in certain measure such as vaccination in order to prevent themselves from potential risk of the contracting diseases. Given that possibility of contracting disease is uncertain, consumer do not make rational decision towards this preventive behavior. This study aims to investigate the persuasion effect depending on how consumer prospect for the future could be moderated by uncertainty of outcome. Experiment 1 was design as framing(gain/loss) × terms of payment(now/later) and this was compared with experiment 2 which designed with uncertainty(high/low). The result show significant interaction effect between framing and term of payment for the loss, paying later was more effective while paying now was more effective for the gain. The interaction effect between framing and uncertainty was proven to be significant as well. It implies that consumer tend to prefer certain but small thing when they gain and uncertain but thing when they lose. Thus, the finding indicate that the persuasion effect of message can be moderated by the terms of payment(when the payment is made), or possibility of the outcome occurrence(possibility of that outcome might come true). These results could be used practically in various related fields.