Grounded on an extended model of blood donation and celebrity identification, this study explored critical factors that help design a health promotion message and strategy. Specifically, the study tested whether collective-efficacy and identification with celebrities increase behavioral intentions to donate blood. American college students were asked to complete items related to blood donation assessing the theory of planned behavior variables of attitude, subjective norm, and perceived behavioral control, as well as self-efficacy, self-identity, altruism, collective-efficacy, identification with a favorite celebrity, and demographics. Results of survey revealed that the intentions to donate blood were significantly affected by collective-efficacy and celebrity identification after controlling for other independent variables and demographics. The study provides implications that theory-based campaigns for blood donation can be effectively devised by the proper selection of messages and celebrity endorsers.